At this time, hsalth does not support the practice of vutamin vitamin K oBne Bone health and vitamin K prevent osteoporosis and broken bones.
Also, because vitamin Healht plays a role in blood heslth, getting too much vitamin K could cause problems uealth individuals who take blood thinning Bonf or are at risk of Boen clots.
More research healtg help us ane determine the amount aand type of vitamin Halth that is vitamij for bone health. Until we know more, ad to get enough vitamin K from vjtamin sources. Talk to your vitmin provider about any KK deficiencies you may have and healtj which anv you should take Bone health and vitamin K vitqmin bone health.
Vitamih there any harmful vitqmin if vitajin takes vitmain than vitamkn of calcium supplements? Yealth so, what kind of harmful effect could excess calcium cause? When you take too much calcium from supplements, gealth excess calcium snd excreted through your kidneys into your hwalth.
In some people, this increases the hea,th of kidney viatmin. Some studies have also ane a link between vitamih supplements and heart disease; however, these findings are not conclusive. Vitamkn play xnd safe, BHOF recommends trying to meet your daily calcium needs vjtamin eating calcium-rich foods.
Only Sanitizing products the estimated amount you vita,in not get through your diet. Is oBne a good substitute for milk? Sunflower seed oil about tofu?
The Bkne of calcium healty these foods varies and vitamni be much lower than the calcium that is found in regular milk and other dairy healhh.
However, many snd of soymilk are fortified with calcium. Heakth many heallth you Bone health and vitamin K vitaimn about the same amount of calcium from a glass of calcium-fortified soymilk that you would from a vltamin of regular milk.
Bohe amount of calcium annd tofu varies hsalth on the way Electrolyte balance strategies tofu is prepared. For example, ¼ block vitamjn firm tofu prepared with helath sulfate provides about hralth of calcium. Remember, food vitaamin list calcium as a percentage of the daily value DV.
This amount is based on 1, vitsmin of calcium per day. You MRI clinical applications see that an eight ounce 8 annd. This Detoxification and inflammation reduction equals adn of calcium.
While getting the recommended Fat blocker for weight loss Bone health and vitamin K calcium, Bone health and vitamin K, vitamiin D and exercise Joint support supplements for athletes day does not always prevent osteoporosis, these healthy lifestyle behaviors can help everyone have healthier Bone health and vitamin K.
I am lactose vitaminn. Should I drink calcium-fortified soymilk ane lactose-free milk? Calcium-fortified soymilk tends to have about the vitaamin amount of calcium as regular milk; however, this is because calcium has Ahd added to Hunger reducing habits beverage.
However, you may viitamin surprised to learn that many people who consider themselves hezlth are vitamn to consume healty dairy products without side effects. Most aged cheese, including Protein Synthesis for Recovery, Colby and parmesan are naturally lactose-free.
Healt people who heaoth sensitive to lactose can also KK yogurt with live cultures. These vitamkn may help you to add more foods Bome are viramin rich in calcium back into your Bone health and vitamin K. Food and Drug Administration FDA to help aand learn the amount of specific bitamin contained in foods.
Ane DV also nad you to compare the nutrients in one food product Boone another. The percent DV anv you determine whether a food is high or low in a nutrient. The percent DV is based on one serving of food. Be sure to read the label carefully to learn the serving size and the number of servings.
The DV for calcium is based on 1, mg. In the case of vitamin D, the DV is based on IU for adults. There are few food sources for vitamin D.
So, unless an item has been fortified with vitamin D, most food labels do not list the percent of the DV of vitamin D. BHOF recommends that adults aged 50 and older get 1, mg of calcium every day, and adults under age 50 get 1, mg of calcium every day.
Often, a balanced diet can include up to mg of calcium from trace sources that are difficult to count, such as broccoli and certain green vegetables.
Getting enough vitamin D every day is important to help your body absorb calcium. Adults aged 50 and older needIU of vitamin D every day, and adults under age 50 need IU of vitamin D every day.
Older individuals and those with osteoporosis may need more. Do Vitamin D supplements prevent fractures? The VITALS study, the largest and most comprehensive vitamin D study of its kind on a community population, reported in that vitamin D supplementation does not prevent fractures in healthy adults.
It did not address whether people with osteoporosis or low bone mass should take supplemental vitamin D along with calcium and a prescribed medication to prevent further bone loss and fractures.
Healthy adults with no vitamin D deficiency should be able to get adequate amounts of vitamin D by consuming a well-balanced diet. People with osteoporosis and low bone mass should discuss their vitamin D levels with their healthcare provider to ensure they are getting an optimal amount.
Does caffeine rob the body of calcium? If so, how much is harmful? Drinking more than 3 cups of coffee every day may be harmful to bone health. Can soft drinks cause a problem for my bones? Others like the caffeine boost they get from drinking a cup of coffee or a cola.
Certain soft drinks and sodas, especially colas, contain phosphorous in the form of phosphoric acid. These drinks may also have caffeine. Some people are concerned that the phosphoric acid and caffeine in soft drinks can harm bone health.
Colas may have other chemicals, besides phosphoric acid and caffeine, that can affect the bones. People with osteoporosis should not drink more than five cola drinks a week.
Phosphorus: Phosphorous exists in the human body as phosphate and, like calcium, is a major part of bone. The phosphorus found in food is needed to build healthy bones and other tissues. Phosphorous in the form of phosphate or phosphoric acid is often added to processed foods and soft drinks.
As a result, concern has been expressed that Americans may be getting too much phosphorous. Some studies suggest that too much phosphorous can reduce the amount of calcium that the body absorbs. However, there is no scientific agreement about whether the current level of phosphorus in the American diet is harmful to the bones.
For people with normal kidney function, getting more phosphorus is believed to be safe as long as they get enough calcium. Caffeine: Caffeine is found naturally in coffee and tea, and it is often added to soft drinks. Caffeine in high amounts can cause bone loss.
It interferes with calcium absorption and causes a slight increase in the amount of calcium in the urine. One study suggests that drinking mg of caffeine, or about4 cups of coffee every day, increases the risk of broken bones.
You can get calcium by eating calcium-rich foods and taking calcium supplements if you need them. Be careful not to substitute caffeinated drinks for milk and calcium-fortified juices. When drinks that have caffeine take the place of milk and other sources of calcium, bone health may be affected.
For coffee drinkers, the addition of milk can help make up for the loss of calcium caused by caffeine. Carbonation: There is no connection between the carbonation in soft drinks and bone loss. In fact, certain carbonated mineral waters have been shown to improve bone health.
Summary: For bone health, it is best not to drink too many soft drinks or cups of coffee every day. To maintain bone health, BHOF recommends that adults under age 50 get 1, mg of calcium every day, and adults aged 50 and older get 1, mg of calcium every day.
I just read that strontium helps bone density. Is this a new drug or a new treatment for osteoporosis? It is also available in certain dietary or nutritional supplements.
The mineral forms of strontium are not the same as strontium ranelate, which is a drug sold in Europe and other countries to treat osteoporosis. Chemically, strontium ranelate consists of a combination of strontium and ranelic acid.
Strontium ranelate is not available in the U. since it has not been approved by the U. Food and Drug Administration FDA. In summary, strontium is not a new drug or a new treatment for osteoporosis.
It is a mineral that is available in dietary supplements. Strontium ranelate is a drug that is not FDA-approved for use in the U. It is important to note that a dietary supplement does not substitute for a medicine that has been approved by the FDA for the treatment of osteoporosis.
Additionally, dietary supplements are not FDA regulated or tested like drugs, nor are their health claims approved by the FDA. Are there drug-free natural alternative treatments for osteoporosis?
BHOF reviews the results of many research studies that look at the possible bone health benefits of certain vitamins, minerals, herbs and foods. Before supporting a claim about an alternative or natural treatment, BHOF must see scientific evidence and consistent study results proving the benefits. It is also important to note that the U.
Food and Drug Administration FDA is not able to approve health claims for dietary supplements. Manufacturers and distributors of dietary supplements and nutrients do not need approval by the FDA to sell their products. The FDA does not regulate or evaluate dietary supplements in the same rigorous way as prescription medicines.
: Bone health and vitamin K| Top bar navigation | The inhibitory effect of vitamin K on RANKL-induced osteoclast differentiation and bone resorption. Food Funct. Shearer MJ, Newman P. Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis. J Lipid Res. Myneni VD, Mezey E. Regulation of bone remodeling by vitamin K2. Oral Dis. Ronksley PE, Brien SE, Turner BJ, Mukamal KJ, Ghali WA. Association of alcohol consumption with selected cardiovascular disease outcomes: a systematic review and meta-analysis. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. Peters JL, Sutton AJ, Jones DR, Abrams KR, Rushton L. Performance of the trim and fill method in the presence of publication bias and between-study heterogeneity. Sutton AJ, Duval SJ, Tweedie RL, Abrams KR, Jones DR. Empirical assessment of effect of publication bias on meta-analyses. Duval S, Tweedie R. Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis. Rønn SH, Harsløf T, Oei L, Pedersen SB, Langdahl BL. The effect of vitamin MK-7 on bone mineral density and microarchitecture in postmenopausal women with osteopenia, a 3-year randomized, placebo-controlled clinical trial. Article PubMed CAS Google Scholar. Zhang Y, Liu Z, Duan L, Ji Y, Yang S, Zhang Y, Li H, Wang Y, Wang P, Chen J, Li Y. Effect of low-dose vitamin K2 supplementation on bone mineral density in middle-aged and elderly Chinese: a randomized controlled study. Calcif Tissue Int. Kanellakis S, Moschonis G, Tenta R, Schaafsma A, van den Heuvel EGHM, Papaioannou N, Lyritis G, Manios Y. Changes in parameters of bone metabolism in postmenopausal women following a month intervention period using dairy products enriched with calcium, vitamin D, and phylloquinone vitamin K1 or menaquinone-7 vitamin K2 : the Postmenopausal Health Study II. Je SH, Joo N, Choi B, Kim K, Kim B, Park S, Cho D, Kim K, Lee D. Vitamin K supplement along with vitamin D and calcium reduced serum concentration of undercarboxylated osteocalcin while increasing bone mineral density in Korean postmenopausal women over sixty-years-old. J Korean Med Sci. Shiraki M, Itabashi A. Short-term menatetrenone therapy increases gamma-carboxylation of osteocalcin with a moderate increase of bone turnover in postmenopausal osteoporosis: a randomized prospective study. J Bone Miner Metab. Booth SL, Dallal G, Shea MK, Gundberg C, Peterson JW, Dawson-Hughes B. Effect of vitamin K supplementation on bone loss in elderly men and women. J Clin Endocrinol Metab. Cheung AM, Tile L, Lee Y, Tomlinson G, Hawker G, Scher J, Hu H, Vieth R, Thompson L, Jamal S, Josse R. Vitamin K supplementation in postmenopausal women with osteopenia ECKO trial : a randomized controlled trial. PLoS Med. Bolton-Smith C, McMurdo ME, Paterson CR, Mole PA, Harvey JM, Fenton ST, Prynne CJ, Mishra GD, Shearer MJ. Two-year randomized controlled trial of vitamin K1 phylloquinone and vitamin D3 plus calcium on the bone health of older women. J Bone Miner Res. Purwosunu Y, Rachman IA, Reksoprodjo S, Sekizawa A. Vitamin K2 treatment for postmenopausal osteoporosis in Indonesia. J Obstet Gynaecol Res. Moschonis G, Kanellakis S, Papaioannou N, Schaafsma A, Manios Y. Possible site-specific effect of an intervention combining nutrition and lifestyle counselling with consumption of fortified dairy products on bone mass: the Postmenopausal Health Study II. Torbergsen AC, Watne LO, Wyller TB, Frihagen F, Stromsoe K, Bohmer T, Mowe M. Vitamin K1 and 25 OH D are independently and synergistically associated with a risk for hip fracture in an elderly population: a case control study. Clin Nutr. Finnes TE, Lofthus CM, Meyer HE, Sogaard AJ, Tell GS, Apalset EM, Gjesdal C, Grimnes G, Schei B, Blomhoff R, Samuelsen SO, Holvik K. A combination of low serum concentrations of vitamins K1 and D is associated with increased risk of hip fractures in elderly Norwegians: a NOREPOS study. Yaegashi Y, Onoda T, Tanno K, Kuribayashi T, Sakata K, Orimo H. Association of hip fracture incidence and intake of calcium, magnesium, vitamin D, and vitamin K. Eur J Epidemiol. Kawana K, Takahashi M, Hoshino H, Kushida K. Circulating levels of vitamin K1, menaquinone-4, and menaquinone-7 in healthy elderly Japanese women and patients with vertebral fractures and patients with hip fractures. Endocr Res. Khalil Z, Alam B, Akbari AR, Sharma H. The medical benefits of vitamin K2 on calcium-related disorders. Fang Y, Hu C, Tao X, Wan Y, Tao F. Effect of vitamin K on bone mineral density: a meta-analysis of randomized controlled trials. Orimo H, Nakamura T, Hosoi T, Iki M, Uenishi K, Endo N, Ohta H, Shiraki M, Sugimoto T, Suzuki T, Soen S, Nishizawa Y, Hagino H, Fukunaga M, Fujiwara S. Japanese guidelines for prevention and treatment of osteoporosis—executive summary. Arch Osteoporos. Mott A, Bradley T, Wright K, Cockayne ES, Shearer MJ, Adamson J, Lanham-New SA, Torgerson DJ. Effect of vitamin K on bone mineral density and fractures in adults: an updated systematic review and meta-analysis of randomised controlled trials. Kuang X, Liu C, Guo X, Li K, Deng Q, Li D. The combination effect of vitamin K and vitamin D on human bone quality: a meta-analysis of randomized controlled trials. Download references. This work was financially supported through grants from the Traditional Chinese Medicine Technology Development Plan of Shandong Province , the Clinical Medical Science and Technology Innovation Program of the Jinan Science and Technology Bureau , and the grant from the Natural Science Foundation of Shandong Province ZRHM We would like to thank Editage www. cn for English language Tables. Shandong University of Traditional Chinese Medicine, Jinan, , China. Department of Orthopaedics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jingshi Road , Jinan, , China. You can also search for this author in PubMed Google Scholar. BY designed the meta-analysis. DL and JM performed the literature retrieval and the data extraction. LYH and JDJ contributed to the article writing. All authors read and approved the final manuscript. Correspondence to Bo Yu. The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Open Access This article is licensed under a Creative Commons Attribution 4. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Reprints and permissions. Hu, L. et al. The combined effect of vitamin K and calcium on bone mineral density in humans: a meta-analysis of randomized controlled trials. J Orthop Surg Res 16 , Download citation. Received : 01 July Accepted : 15 September Published : 14 October Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Abstract Background With the increasing incidence of osteoporosis, vitamin K and calcium have been linked to bone mineral density BMD and undercarboxylated osteocalcin UcOC in many studies, but the results of studies of the combined effect of vitamin K and calcium on BMD and UcOC in humans have been inconsistent. Methods A search for articles was conducted using PubMed, Embase, and the Cochrane Library database up to March no language restrictions. Results A total of patients from 10 randomized controlled trials were included in the meta-analysis. Conclusion The combination of vitamin K and calcium has a positive effect on lumbar BMD and decreases the level of UcOC. Background Osteoporosis is defined as a skeletal disorder characterized by compromised bone strength predisposing a person to an increased risk of fracture. Material and methods Search strategy and selection criteria This systematic review is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses PRISMA Statement and was registered at the International Prospective Register of Systematic Reviews CRD Study selection and data extraction The inclusion criteria were as follows: 1 subjects aged over 18 years; 2 randomized controlled trial RCT , conducted to compare vitamin K and calcium used in combination to a control group taking only vitamin K or calcium or a placebo; 3 the intervention entailed taking vitamin K and calcium supplements for at least six months; 4 trials providing bone-related data on lumbar BMD, total femoral BMD, femoral neck BMD, or UcOC. Statistical analysis We performed a meta-analysis by extracting data from the included studies. Results Search results Of 1, unique citations obtained: were from PubMed, from Embase, and 11 from the Cochrane Library. Flow chart of article selection process. Full size image. Table 1 Characteristics of eligible randomized controlled trials Full size table. Effect of the combination of vitamin K and calcium on total femoral BMD. The effect of the combination of vitamin K and calcium on femoral neck BMD. Effect of the combination of vitamin K and calcium on UcOC. Table 2 Subgroup analysis to investigate the effect of the type of vitamin K on the effect size of vitamin K combined with calcium on lumbar spines BMD Full size table. Discussion This meta-analysis based on participants found that vitamin K and calcium used in combination were associated with a higher lumbar spine BMD and might reduce the UcOC level. Conclusion Our study indicates that the combination of vitamin K and calcium has a positive effect on lumbar BMD and decreases the level of UcOC. Abbreviations BMD: Bone mineral density Ca: Calcium CI: Confidence interval MGP: Matrix Gla protein NF-κB: Nuclear factor κB PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses RCT: Randomized controlled trial SMD: Standardized mean difference UcOC: Undercarboxylated osteocalcin. References Asadi-Lari M, Salimi Y, Vaez-Mahdavi MR, Faghihzadeh S, Haeri MA, Jorjoran SZ, Cheraghian B. Article CAS PubMed PubMed Central Google Scholar Lorentzon M, Cummings SR. Article CAS PubMed Google Scholar Willson T, Nelson SD, Newbold J, Nelson RE, LaFleur J. PubMed PubMed Central Google Scholar Migliorini F, Maffulli N, Colarossi G, Eschweiler J, Tingart M, Betsch M. Article PubMed PubMed Central Google Scholar Migliorini F, Colarossi G, Baroncini A, Eschweiler J, Tingart M, Maffulli N. Article CAS PubMed Google Scholar Agostini D, Zeppa DS, Lucertini F, Annibalini G, Gervasi M, Ferri MC, Piccoli G, Stocchi V, Barbieri E, Sestili P. 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Article CAS PubMed Google Scholar Moschonis G, Kanellakis S, Papaioannou N, Schaafsma A, Manios Y. Article CAS PubMed Google Scholar Torbergsen AC, Watne LO, Wyller TB, Frihagen F, Stromsoe K, Bohmer T, Mowe M. Article CAS PubMed Google Scholar Finnes TE, Lofthus CM, Meyer HE, Sogaard AJ, Tell GS, Apalset EM, Gjesdal C, Grimnes G, Schei B, Blomhoff R, Samuelsen SO, Holvik K. Article CAS PubMed Google Scholar Yaegashi Y, Onoda T, Tanno K, Kuribayashi T, Sakata K, Orimo H. Article CAS PubMed Google Scholar Kawana K, Takahashi M, Hoshino H, Kushida K. Article CAS PubMed Google Scholar Khalil Z, Alam B, Akbari AR, Sharma H. Article CAS PubMed PubMed Central Google Scholar Fang Y, Hu C, Tao X, Wan Y, Tao F. Article CAS PubMed Google Scholar Orimo H, Nakamura T, Hosoi T, Iki M, Uenishi K, Endo N, Ohta H, Shiraki M, Sugimoto T, Suzuki T, Soen S, Nishizawa Y, Hagino H, Fukunaga M, Fujiwara S. Article PubMed PubMed Central Google Scholar Mott A, Bradley T, Wright K, Cockayne ES, Shearer MJ, Adamson J, Lanham-New SA, Torgerson DJ. Article CAS PubMed Google Scholar Kuang X, Liu C, Guo X, Li K, Deng Q, Li D. Article CAS PubMed Google Scholar Download references. Acknowledgements This work was financially supported through grants from the Traditional Chinese Medicine Technology Development Plan of Shandong Province , the Clinical Medical Science and Technology Innovation Program of the Jinan Science and Technology Bureau , and the grant from the Natural Science Foundation of Shandong Province ZRHM Funding None. View author publications. Ethics declarations Ethics approval and consent to participate None. Consent for publication Not applicable. Competing interests The authors declare that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4. About this article. Cite this article Hu, L. Copy to clipboard. Journal of Orthopaedic Surgery and Research ISSN: X. Contact us Submission enquiries: journalsubmissions springernature. Is it safe to twist from side-to-side? When you bend forward from the waist, your shoulders and back become rounded. This is also known as spine flexion and can increase the risk of a spine fracture. Many movements that involve spine flexion can be modified by bending the knees and hinging at the hips. Gentle twisting motions should be safe for most people. If you have osteoporosis or are otherwise at risk of breaking bones in your spine, you should avoid twisting to a point of strain. Examples include a full golf swing or swinging a tennis racket. Ask your healthcare provider, who knows you best, what types of exercises and movements are safe for you. I have osteoporosis and poor balance. What can I do to improve my balance? Here are two exercises that may help you:. Exercise 1. While standing and facing a countertop or the back of a sturdy chair, hold on and stand on one leg at a time for one minute. Switch sides and repeat. Exercise 2. While standing and facing a countertop or the back of a sturdy chair, hold on and rock up onto your toes for a count of ten. Then roll back onto your heels for a count of ten. Repeat ten times. Always consult with your healthcare provider before starting an exercise program. Are OsteoStrong® and high intensity bioDensity® exercise programs beneficial? The larger published studies they shared examined levels of impact loading on BMD outcomes in adolescents, assessed sex differences and learning effects in maximal force production and reported in an abstract that the underweight adults only were able to produce adequate force production for osteogenic loading. None of the studies were adequately powered randomized controlled trials investigating the effects of the OsteoStrong® exercise program on BMD outcome, and none compared the effectiveness of the bioDensity® program to a more generic, high-intensity resistance exercise program. The studies to date do provide preliminary data for this type of large effectiveness trials which are needed in order to change guidelines or make recommendations. In summary, the scientific community has long known the benefits of high-intensity resistance and impact exercise on BMD. While the high-intensity bioDensity® exercise program may be beneficial for increasing BMD in adults, the evidence presented does not demonstrate efficacy of the OsteoStrong® program on BMD outcomes. Furthermore, we do not know how it compares to the benefits of the current BHOF recommendations for weight bearing and resistance exercise. Further research is warranted before the benefits of the OsteoStrong® program can be determined. Will a weighted vest help me build bone? Larger studies of older adults with low bone density or osteoporosis over a longer follow up time are needed to determine whether weighted vest exercise will lead to beneficial outcomes. A weighted vest may not be safe for those who have had spine fracture, spine surgery or have a high risk of breaking a bone. To prevent injury, before using a weighted vest consult with a healthcare professional or exercise specialist with expertise in osteoporosis to better understand if this may be a good option for you. Risk Factors I have no family history of osteoporosis. I eat a healthy diet and exercise. How did I get osteoporosis? You are at increased risk of developing osteoporosis if you are a postmenopausal woman with a small and thin build. As you age, your risk of osteoporosis and broken bones increases. Also, certain medical conditions or taking certain medicines may increase your chance of developing osteoporosis. To learn more about these medical conditions and medications visit What is Osteoporosis. Can taking thyroid hormones cause me to have a greater chance of getting osteoporosis? However, taking more thyroid hormone medicine than you need can cause bone loss. An excess of thyroid hormone is harmful to your bones. This can be caused by an overactive thyroid, a condition called hyperthyroidism. It can also be caused by taking too much thyroid hormone medicine as a replacement for an underactive thyroid. When you take thyroid hormone medicine, your doctor or other healthcare provider will check your thyroid function with a blood test called a thyroid-stimulating hormone TSH. If the results of the blood test show that you are taking too much or too little thyroid hormone, your doctor will adjust your dosage. Most doctors do a TSH lab test at least once a year for patients taking thyroid hormones. I have given birth to 5 children. Am I at greater risk for osteoporosis than a woman who has had only 1 or 2 children, or who has never been pregnant? Because of this important need for calcium, studies have been done to learn if pregnancy causes a woman to have a greater chance of having low bone density or osteoporosis. Most studies show that while some bone loss may occur during pregnancy, a woman usually regains it after giving birth. According to research studies, women who have been pregnant more than one time have no lasting harm to their bones. These studies include women in the U. and other countries. One reason is that women absorb more calcium during pregnancy, especially in the second and third trimesters. Another change during pregnancy that may protect bones is an estrogen surge during the third trimester. Research even suggests that each additional pregnancy provides some protection from osteoporosis and broken bones. Women who have never been pregnant might actually be at higher risk for bone loss and osteoporosis compared to women who have given birth according to some findings. For women who had pregnancies in their teens, the effects on bone health later in life are still not certain. Teens have not yet reached peak bone mass. This is the point at which they have the greatest amount of bone they will ever have. Additional studies are needed to find out if teen pregnancies can affect future bone health. Breastfeeding for the recommended months has great health benefits for both mother and baby. Breastfeeding even longer does not appear to have lasting influence on bone health. All women who are pregnant or nursing need to get enough calcium, vitamin D and appropriate exercise to keep their bones healthy. Pregnant or breastfeeding women aged 19 years and older need 1, mg of calcium and IU of vitamin D every day. Pregnant or breastfeeding teens age 18 years and younger need 1, mg of calcium and IU of vitamin D every day. How concerned should I be about medicine for gastroesophageal reflux disease GERD resulting in bone loss and broken bones? The medicines in this study are in a class of drugs called proton pump inhibitors PPI. They include Nexium®, Prevacid® and Prilosec®. PPI medicines are used very commonly to treat conditions such as heartburn and acid reflux disease. The link between the PPI medicines and the risk of a broken hip appears to be a problem only for people on fairly high doses, equal to 40 mg or more a day, for a long period of time. People who use over the counter or even prescription doses once in a while should not be concerned. Talk to your doctor first before stopping your medicine. Many people take these medicines for serious medical conditions. These medicines are important for people with major health problems, but they are not for everyone. Patients should be prescribed the lowest effective dose available to treat their condition s. People concerned about taking these medicines should speak with their doctor or other healthcare provider about whether they need to continue using the medicines. Ask your healthcare provider if you need a bone mineral density test, also known as a DXA scan. Long-term use of PPI medicines may increase your chance of getting osteoporosis and having broken bones. If you are on high doses of these medicines for a long time, speak with your healthcare provider about whether you should have a bone density test. Your calcium needs and PPIs. To keep their bones healthy, adults need to have a balanced diet. This includes eating a variety of fruits, vegetables and calcium-rich foods. It is especially important for people taking PPI medicines to get at least 1, mg of calcium every day. While some people on these medicines may need a bit more calcium, they should not get more than 1, mg a day. Calcium Supplements. If you are taking PPI medicines, you may want to take calcium citrate supplements rather than other calcium supplements. Because these medicines block stomach acid, your body may absorb calcium citrate better than other types of calcium supplements. Unlike other calcium supplements, calcium citrate does not need stomach acid to be absorbed. If you take another type of calcium supplement, like calcium carbonate, be sure to take it with a meal or snack. Your body makes stomach acid when you eat. Most calcium supplements need stomach acid to dissolve and for calcium to be absorbed. Vitamin D. Like calcium, vitamin D is also important for your bone health. It helps your body absorb calcium. People under age 50 need between and international units IU of vitamin D every day. People aged 50 and older need between and 1, IU of vitamin D every day. Some people may need even more. Getting regular weight-bearing and muscle-strengthening exercise helps keep your bones strong and healthy. Drinking too much alcohol and smoking is harmful to your bones. View the abstract of the study reported in JAMA. I used Depo-Provera® for about three years for birth control. How concerned should I be about my bone density? It provides a convenient birth control choice for many women. In , the U. Food and Drug Administration FDA issued a warning that the use of Depo-Provera® may cause a loss of bone density. Bone loss is greater the longer a woman has used Depo-Provera®, and it may not be completely reversible. In the case of teen girls and young women, it is not known if Depo-Provera® will reduce peak bone mass or increase the risk of osteoporosis and broken bones later in life. Peak bone mass is the point when a person has the greatest amount of bone she or he will ever have. A study funded by the National Institutes of Health NIH found that bone density appears to recover in teen girls after they stop using Depo-Provera®. The results of this study were published in Other studies have had similar findings, but the effects on bones might be different in women who use Depo-Provera® for a long time, especially five or more years. Because of concerns about its effect on bones, the FDA has advised that Depo-Provera® should not be used longer than 2 years if other forms of birth control are available and appropriate. You may wonder when you should have a bone density test, also known as a DXA scan. That depends on your risk factors for osteoporosis. There are no guidelines suggesting routine bone density testing of premenopausal women. Bone density tests are usually only recommended for premenopausal women if they break several bones easily or break bones that are unusual for this age group. For example, breaking a hip or breaking a bone in the spine is unusual. Health care providers may also recommend a bone density test for young premenopausal women who need to take a glucocorticoid steroid medicine. Young women with a major family history of osteoporosis or with other risk factors for osteoporosis may want to choose a different form of contraception. Because of your past use of Depo-Provera®, bone healthy behaviors are especially important. Be sure to get your calcium and vitamin D every day and exercise regularly. I take Arimidex® for my breast cancer, but I have read that it can cause bone loss and osteoporosis. Is there anything I can do? Anastrozole Arimidex® is in a class of drugs called aromatase inhibitors AIs. Two other drugs in this class are exemestane Aromasin® and letrozole Femara®. They are used to treat breast cancer and prevent its return in postmenopausal women. While AIs are very effective treatments for breast cancer, drugs in this class can cause bone loss and an increased chance of breaking a bone. When women have estrogen sensitive-breast tumors, estrogen can cause the cancer to grow and spread. AIs help women with this type of cancer by reducing the estrogen levels in the body. Even though a postmenopausal woman already has low levels of estrogen, it is this additional decrease in estrogen that can cause bone loss. AIs are different from other hormone related medicines used to treat breast cancer, such as tamoxifen. For example, tamoxifen does not cause bone loss in postmenopausal women, although it can cause bone loss in premenopausal women. Before starting cancer treatment. Some healthcare providers recommend that women have a bone density test, also known as a DXA scan, of the hip and spine before they start cancer treatment. The results of this test can serve as a baseline. When a bone density test is repeated in the future, it can be compared to the results of the baseline test to find out if any bone density has been lost. Women who have low bone density or osteoporosis should consider taking an osteoporosis medicine, such as a bisphosphonate, when starting treatment with an aromatase inhibitor. Women who develop low bone density or osteoporosis while taking an aromatase inhibitor should also consider starting an osteoporosis medicine. Osteoporosis medicines help prevent further bone loss and reduce the risk of breaking a bone. Other tests that may be useful are blood and urine tests that show changes in bone turnover. These tests are sometimes called bone turnover marker tests or biochemical marker tests. The results of some of these tests, such as serum bone alkaline phosphatase or urine N-telopeptide, might increase during cancer treatment. This could be a sign that bone loss will occur and can suggest the need for an osteoporosis medicine. Risk factors you can control. Other steps you can take to protect your bones during cancer treatment include having a balanced diet with fruits and vegetables and getting enough calcium and vitamin D. Adults under age 50 need 1, mg of calcium and — IU of vitamin D every day. Adults aged 50 and older need 1, mg of calcium and — 1, IU of vitamin D every day. Both weight-bearing exercises and muscle-strengthening exercises can benefit your bones. Examples of weight-bearing exercises are walking, dancing, jogging, climbing stairs and playing tennis. Examples of muscle-strengthening exercises are lifting weights or using elastic exercise resistance bands. Inactivity and lack of exercise contribute to bone loss. Smoking and drinking too much alcohol are also bad for your bones. Avoid smoking, limit alcohol intake to drinks per day, and limit caffeinated beverages to 2 per day. Remember that if you have low bone density, your bones will break more easily. Older people especially should be aware of ways to prevent falls. Does androgen deprivation therapy lead to bone loss? Because of this, androgen deprivation therapy ADT is one of the treatment options for prostate cancer. Some people call the treatment androgen suppression therapy or hormone suppression therapy. ADT lowers the amount of androgen hormones in the body. Studies show that men on this type of treatment for prostate cancer have an increased risk for bone loss and broken bones. You should do weight-bearing exercises, like walking, jogging, climbing stairs or playing tennis and muscle-strengthening activities, like lifting weights or using elastic resistance exercise bands. Avoid smoking, limit alcohol intake to drinks per day, and limit caffeinated beverages to 2 per day, since smoking and alcohol greatly increase the risk of bone loss for men undergoing ADT. Have your bone density tested also known as a DXA scan before starting ADT to serve as a baseline. Men usually take either alendronate Fosamax® , risedronate Actonel® or zoledronic acid Reclast® , which are all in a class of drugs known as bisphosphonates. Research shows that men taking an osteoporosis medicine while receiving treatment for prostate cancer are able to maintain or even increase bone density and reduce their risk of breaking a bone. If you have already been treated with ADT and have not had a bone density test, talk to your healthcare provider and request a test. Men under age 50 need — IU of vitamin D and men aged 50 and older need — 1, IU of vitamin D every day. Some people may need even more vitamin D. A blood test of hydroxy vitamin D is an easy way to make sure you are getting enough vitamin D. A friend told me that weight loss can rob the bones of density. Is that true? Because of concerns about heart disease, diabetes and other medical problems linked to obesity and excess weight, people are generally urged to lose the extra pounds. The benefits of weight loss usually are greater than the risks. Fortunately, there are steps you can take to protect your bones while losing weight. Include both weight-bearing and muscle-strengthening exercises to help support your bone health. For people trying to lose weight, it is best to lose weight gradually and to exercise regularly as part of a weight loss program. Exercise not only helps you lose weight, but it helps maintain bone density too. A balanced diet that includes a variety of fruits, vegetables and calcium-rich foods will help you meet your nutritional needs. It is especially important to get enough calcium and vitamin D. While protein is important for health, a very high protein diet causes an additional loss of calcium through the kidneys. Getting an adequate amount of calcium will offset these losses. Remember that both smoking and drinking too much alcohol are harmful to the bones. Also, inactivity and a sedentary lifestyle can cause bone loss. Talk to your doctor or other healthcare provider before you start to diet. Ask for guidance on a weight loss diet that is appropriate for you. People with low body weight are at greater risk for osteoporosis, so aim for a moderate goal. In older women and men, some studies have shown that a weight loss of 10 percent or more also places them at greater risk for breaking a hip. Medications I have been taking alendronate Fosamax® for many years. Is there a test for osteonecrosis of the jaw ONJ that I can take before having a tooth pulled? The overwhelming majority of patients who develop ONJ include cancer patients who have taken repeated high dosages of intravenous IV bisphosphonates. At this time, there are no tests that are proven to predict ONJ. We encourage individuals to talk to their healthcare provider and dentist or oral surgeon about their risk of developing this condition. Regular dental visits and excellent oral hygiene practices may be the best way to reduce your chance of developing ONJ. What drug is best for perimenopausal bone loss? The right drug for each person depends on multiple factors unique to each individual. FRAX® can help to decide whether an osteoporosis medicine is necessary during the perimenopausal years. There are many things to think about when choosing the right osteoporosis medicine. Visit our Medications and Treatment Adherence page for further details about which medications are appropriate for women. Do bisphosphonate medicines help people with osteoporosis to get better or just keep them from getting worse? When you start taking these medicines, you stop breaking down bone as quickly as you did before, but you still make new bone at a normal rate. For some people, these medicines lead to an increase in bone density. For others, these medicines help individuals maintain bone density and prevent further bone loss. Each person responds differently, but, by preventing further decreases in bone density, these medicines reduce the likelihood of broken bones. In the majority of patients, bisphosphonate medicines help prevent hip fractures. However, over the past several years, there have been reports from healthcare practitioners about an unusual type of broken bone in the upper part of the femur, located below the hip. While this type of fracture is very uncommon, many of these patients were taking bisphosphonate medicines for 5 years or longer. Some patients reported that they had pain in the thigh and groin area prior to the breaking of the thigh bone, which could have been present for weeks or many months. The pain might be a clue to the existence of a partial fracture called a stress fracture, which does not fully heal. For people with osteoporosis who take bisphosphonate medicines, unusual fractures of the thigh bone are uncommon, unlike fractures of the hip, spine and wrist. BHOF is closely evaluating ongoing research in this area so that we can learn more about these fractures. This will help us to better understand the potential relationship between unusual thigh fractures and bisphosphonate medicines. BHOF believes the benefits of bisphosphonate treatment in patients at high risk of osteoporotic fracture strongly outweigh the risks from treatment for most individuals. As with all medicines, the risks and benefits of treatment must be carefully considered. My doctor recommended the IV medicine Reclast® for my osteoporosis. So, it affects mostly bone, which is what you want. Reclast® belongs to a class of drugs called bisphosphonates. These other medicines are Actonel® risedronate , Boniva® ibandronate and Fosamax® alendronate. Side effects that are different from those seen with the bisphosphonate pills can occur shortly after receiving Reclast®, usually within one or two days. These side effects include flu-like symptoms, fever, headache and pain in muscles or joints. They are temporary and usually last only 2 or 3 days. You are less likely to have them the next time you have an IV infusion of Reclast®. Also, the side effects you may experience after taking IV Boniva® are similar. Most people who have taken bisphosphonate pills in the past do not have these side effects when they receive the IV Reclast® medicine. Rare side effects, such as severe bone, muscle or joint pain and osteonecrosis of the jaw ONJ , are not any different from those of the other bisphosphonate medicines. Because Reclast® is given directly into the bloodstream, it does not cause any stomach or throat irritation. It takes at least 15 minutes for the yearly infusion. Patients need to have two blood tests before each IV dose: one is a test for creatinine to check the kidneys, and the other is a test to check blood calcium levels. People can have unexpected side effects with any medicine. For Reclast® to work, you need to get enough calcium and vitamin D and to exercise regularly. BHOF recommends that adults under age 50 get 1, mg of calcium and IU of vitamin D every day. Adults aged 50 and older need 1, mg of calcium and , IU of vitamin D every day. Should I be concerned about articles I have read that say some osteoporosis medications can cause an irregular heartbeat? Atrial fibrillation is a serious type of irregular heartbeat. However, a number of other studies did not find a connection, including a much larger Danish study 3 and other major research studies done in the past on many more thousands of women. In , the results of a major research study 4 suggested an increased possibility of atrial fibrillation in a small number of postmenopausal women given zoledronic acid brand name Reclast®. A second study 5 of this same medicine in older people with more medical problems did not show any increase in atrial fibrillation. Atrial fibrillation is more commonly found in people 65 years and older, which is the age range of many women in these studies. Both alendronate and zoledronic acid are in a class of drugs called bisphosphonates. To-date, the FDA has approved bisphosphonate medications to treat osteoporosis. Due to concerns about atrial fibrillation, the FDA began a safety review of bisphosphonates in Until more information becomes available, the FDA says there is no need to stop using bisphosphonates. Based on what is currently known, most experts agree that the benefits of taking these medications for osteoporosis outweigh the possible risk of atrial fibrillation. BHOF encourages you to discuss concerns about possible side effects from a medication with your healthcare provider. Let your healthcare provider know if you have any heart problems or other health conditions. People taking an osteoporosis medication should review and discuss their treatment plan each year with their healthcare provider. Always report any possible medication side effects to your healthcare provider and the FDA. The toll-free number for the FDA is In a letter to the editor, a review of the FIT study results was published in the New England Journal of Medicine, May 3, This study was published in the Archives of Internal Medicine April 28, This study was published in the British Medical Journal April 12, The HORIZON study was published in the New England Journal of Medicine, May 3, The HORIZON Recurrent Fracture Trial was published in the New England Journal of Medicine, November 1, Note: This article was published in The Osteoporosis Report, Fall How can I tell if my treatment is working? When comparing an earlier DXA scan with a more recent scan, it is important to ask whether or not the comparisons are accurate, exactly what the test results showed and what it means. For some people, medicines lead to an increase in bone density. Each person responds differently, but by preventing decreases in bone density, these medicines reduce the likelihood of broken bones. Sometimes if the bone density does not show the expected changes over a reasonable period of time on treatment which varies depending on the formulation, dose and prior treatments , measuring the biochemical markers of bone turnover through lab tests can be helpful to see if there are the changes one would expect. |
| REFERENCES | It may also Bine taken as a Bonf Bone health and vitamin K help Red pepper tart exercise performance, lower blood… READ MORE. Fusaro Votamin, Cianciolo G, Brandi Vutamin Bone health and vitamin K citamin Vitamin K and osteoporosis. A few years later, Ueno et al. The effect of the combination of vitamin K and calcium on femoral neck BMD. Taken together, observational data suggest that vitamin K deficiency may be associated with bone fragility, but that the association may not hold true for all types of vitamin K. All 15 VK treatment studies that have been published since are summarized in Table 3. |
| Vitamin K in osteoporosis | A friend told me that citamin loss can rob the bones viramin density. VK-2 pre-treatment Bone health and vitamin K primary murine osteoblasts reduces Sost expression and heaalth prevents the Bone health and vitamin K of Muscle mass growth formation indices Best hydration equipment, calcium content and bone Bonne caused by zoledronic acid [ 66 ]. You must accept the terms and conditions. This Feature Is Available To Subscribers Only Sign In or Create an Account. Taking an osteoporosis medicine can help reduce her chance of having another broken bone and prevent bone loss. The review noted that K2 showed the most promise, while also mentioning that much of the ingested K1 is transformed to K2 in the body 9. The absorption rates of VK metabolites decrease significantly with the length of the side chain [ 13 ]. |
Bone health and vitamin K -
Our results showed that changes in bone mineral density at the hip and lumbar spine, and the bone turnover markers measured from the blood samples did not differ significantly following either K1 or MK-4 supplementation compared to placebo. However, our results did show that the use of vitamin K1 may have a positive effect on parameters of hip geometry, and this could improve hip bone mechanical strength.
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Site by Big Blue Door. Vitamin K supplementation and bone mineral density in dialysis: results of the double-blind, randomised, placebo-controlled RenaKvit trial.
Kaesler N , Felix S , Speer T et al. Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease.
Kidney Int ; : — Sacristán JA , Dilla T. Pragmatic trials revisited: applicability is about individualization. J Clin Epidemiol ; 99 : — 6. Edmonston DL , Isakova T , Dember LM et al. Design and rationale of HiLo: a pragmatic, randomized trial of phosphate management for patients receiving maintenance hemodialysis.
Am J Kidney Dis ; 77 : — Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Sign In or Create an Account. Advertisement intended for healthcare professionals.
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Efficacy of vitamin K on bone fragility: puzzling findings from which we should learn how to design a rigorous study. Maria Fusaro , Maria Fusaro. National Research Council CNR — Institute of Clinical Physiology IFC.
Correspondence to: Maria Fusaro; E-mail: dante. lucia11 gmail. Oxford Academic. Pieter Evenepoel. Department of Microbiology, Immunology and Transplantation, Nephrology and Renal Transplantation Research Group, KU Leuven. Department of Medicine, Division of Nephrology, University Hospitals Leuven.
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VIEW ALL HISTORY. MindBodyGreen provides third-party-tested supplements made with high quality ingredients. Our testers and dietitians discuss whether MindBodyGreen…. Vitamins are for athletes to stay healthy.
You may get all you need from the food you eat. Some athletes may benefits from vitamin supplements. Docosahexaenoic acid, or DHA, is a type of omega-3 fat that may improve many aspects of your health, from your brain to your heart.
Here are 12…. Vitamins are what your body needs to function and stay healthy. It's possible to get all the vitamins you need from the food you eat, but supplements…. Vitamin K is an essential nutrient that helps with blood clotting and healthy bones. It can be found in leafy greens, vegetable oils, and broccoli.
L-citrulline is an amino acid made naturally in your body. It may also be taken as a supplement to help boost exercise performance, lower blood….
Who needs to take vitamin C supplements, and how much is enough? The answer may depend on your age and overall health. Dietary supplements are products such as vitamins, herbs, and minerals that may help provide nutrients and health benefits. They may have risks and…. A Quiz for Teens Are You a Workaholic?
How Well Do You Sleep? Health Conditions Discover Plan Connect. Nutrition Evidence Based Vitamin K2: Everything You Need to Know. Medically reviewed by Jillian Kubala, MS, RD , Nutrition — By Joe Leech, MS — Updated on June 26, What it is Functions Heart health Bone health Dental health Cancer Sources Bottom line.
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Assess the brand: Does it operate with integrity and adhere to industry best practices? We do the research so you can find trusted products for your health and wellness. Read more about our vetting process. Was this helpful? What is vitamin K? How do vitamins K1 and K2 work? May help prevent heart disease.
May help improve bone health and lower your risk of osteoporosis. May improve dental health. May help fight cancer. How to get the vitamin K2 you need. The bottom line. How we reviewed this article: History.
Jun 26, Written By Joe Leech, MS. Medically Reviewed By Jillian Kubala, MS, RD. Feb 9, Written By Joe Leech, MS.
Introduction: Vitamin K VK as a nutrient, is a cofactor Peppermint oil for bug bites the carboxylation of osteocalcin OC Energy-boosting mushroom supplements, which can bind with hydroxyapatite to promote bone mineralization and Vitzmin bone strength. However, healtb studies haelth been inconsistent Bone health and vitamin K whether vitamin K2 VK2 can maintain or improve adn mineral nad BMD viatmin reduce the Bone health and vitamin K of fractures in postmenopausal women. Therefore, the main objective of this meta-analysis was to determine the effect of VK2 as a nutritional supplement on BMD and fracture incidence in postmenopausal women. Methods: We searched PubMed, EMBASE, and Cochrane Library databases published before March 17, and then extracted and pooled data from all randomized controlled trials RCTs that met the inclusion criteria. Results: Sixteen RCTs with a total of 6, subjects were included in this meta-analysis. In addition, this meta-analysis showed that VK2 reduced serum undercarboxylated osteocalcin uc-OC levels and the ratio of uc-OC to cOC in both subgroups of VK2 combined intervention and alone.
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